There were no ninth inning heroics or controversial calls in this game. Both starting pitchers, Adam Wainwright, for St. Louis and Jon Lester, for Boston, lived up to their reputations and this game was a classic pitchers dual. Boston scored one run in the first inning, and Lester gave up a towering home run to straight away center field by Matt Holliday in the fourth, but that was score, 1 to 1 until Boston took the lead for good in the seventh inning, scoring two runs, one on an Ellsbury RBI single.
Boston Red Sox relief pitcher Koji Uehara came into the game with two outs in the bottom of the eighth inning and retired all four batters he faced, and the Boston Red Sox beat the St. Louis Cardinals by a score of 3 to 1. The teams now head back to Boston for Game 6 Wednesday night, with Boston holding a commanding three games to two games advantage in the best of seven series.